Table 1 Characteristics of transgenic mouse lines.
From: Effective CRISPR interference of an endogenous gene via a single transgene in mice
Line/Founder | Tooth eruption | Skeletal phenotype |
---|---|---|
157 | no | Osteopetrotic |
160 | yes | Normal |
165 | yes | Normal |
167 | yes | High bone mass |
172 | yes | High bone mass |
174 | yes | No germline transmission |
176 | no | Osteopetrotic; founder died before breeding |
178 | Yes | Normal |