Figure 6 | Scientific Reports

Figure 6

From: Maternal overnutrition during critical developmental periods leads to different health adversities in the offspring: relevance of obesity, addiction and schizophrenia

Figure 6

Experimental design illustrating the breeding scheme and dietary pattern. Control (CTR) dams are maintained on standard laboratory chow diet during preconception, gestation and lactation. In case of high-fat diet (HFD) exposure, dams were exposed to HFD during specific periods of gestation and lactation. In the preconception (PC) group, mothers are fed HFD 3 weeks prior to conception. In the early (EG) and late (LG) gestation groups, dams are exposed to HFD during GD0–11 or during GD 12-21, respectively. In the lactation (Lact) group, mothers are fed HFD only during the lactation period. Offspring from all groups are maintained on standard chow diet from weaning and throughout adulthood. GD = gestation day; P = Postnatal day.

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