Table 5 Univariable and Multivariable Cox-Regression Analyses.
From: Follistatin impacts Tumor Angiogenesis and Outcome in Thymic Epithelial Tumors
Univariable Analysis | Multivariable Analysis | |||||
|---|---|---|---|---|---|---|
HR | p-value | 95% CI | HR | p-value | 95% CI | |
Freedom From Recurrence | ||||||
Histology (TC vs. Thymoma) | 6.10 | 0.002 | 1.89–19.61 | 2.08 | 0.317 | 1.99–8.40 |
Tumor Stage (III-IV vs. I-II) | 6.10 | 0.003 | 1.85–20.0 | 1.86 | 0.392 | 0.45–7.75 |
Myasthenia Gravis (neg. vs. pos.) | 1.19 | 0.761 | 0.27–2.62 | |||
Sex (female vs. male) | 0.76 | 0.623 | 0.26–2.27 | |||
Immature Vessels (low vs. high) | 14.8 | 0.010 | 1.90–114.8 | 35.3 | 0.021 | 1.70–734.1 |
Mature Vessels (high vs. low) | 1.42 | 0.550 | 0.45–4.52 | |||
Total Nr. of Vessels (low vs. high) | 6.48 | 0.016 | 1.41–29.8 | 0.24 | 0.220 | 0.02–2.35 |
Activin A (high vs. low) | 33.3 | 0.599 | 0.0–100.0 | |||
Follistatin (high vs. low) | 100.0 | 0.510 | 0.0–100.0 | |||
Cause Specific Survival | ||||||
Histology (TC vs. Thymoma) | 15.2 | 0.002 | 2.73–83.3 | 3.36 | 0.178 | 0.58–19.61 |
Tumor Stage (III-IV vs. I-II) | 500 | 0.212 | 0.36–100.0 | 1.00 | 0.930 | 0–100.0 |
Myasthenia Gravis (neg. vs. pos.) | 2.11 | 0.496 | 0.25–18.1 | |||
Sex (female vs. male) | 0.36 | 0.233 | 0.07–1.94 | |||
Immature Vessels (low vs. high) | 81.2 | 0.235 | 0.06–100.0 | |||
Mature Vessels (high vs. low) | 0.65 | 0.639 | 0.11–3.91 | |||
Total Nr. of Vessels (low vs. high) | 75.6 | 0.241 | 0.06–100.0 | |||
Activin A (high vs. low)* | — | — | — | |||
Follistatin (high vs. low)* | — | — | — | |||
