Figure 7
From: New insight into the mechanisms of ectopic fat deposition improvement after bariatric surgery

Pioglitazone or metformin decreased lipid droplet accumulation in human primary hepatocyte cultures. Panel (A): Nile Red staining of untreated hepatocyte primary culture. Panel (B): Nile Red staining of primary hepatocytes cultured for 24 h in the presence of high levels of oleic acid, glucose and insulin. Panel (C): Nile Red staining of primary hepatocytes cultured for 24 h in the presence of high levels of oleic acid, glucose, insulin and pioglitazone. Panel (D): Nile Red staining of primary hepatocytes cultured for 24 h in the presence of high levels of oleic acid, glucose, insulin and metformin.