Table 1 The comparison of clinical and laboratory parameters between study groups at baseline and the end of study.
Baseline | 12 months | |||||
---|---|---|---|---|---|---|
TA-OH/ECW <15% (n = 120) | TA-OH/ECW ≥15% (n = 31) | p value | TA-OH/ECW <15% (n = 120) | TA-OH/ECW 15% (n = 31) | p value | |
Age | 53.5 ± 12.8 | 55.8 ± 9.0 | 0.342 | |||
Sex (male) (%) | 66 (55.0) | 16 (51.6) | 0.736 | |||
BMI (Kg/m2) | 24.5 ± 3.4 | 23.9 ± 4.0 | 0.419 | |||
DM (%) | 43 (35.8) | 26 (83.9) | <0.001 | |||
Hypertension (%) | 96 (80.0) | 26 (83.9) | 0.626 | |||
Cause of ESRD (%) | 0.001 | |||||
DM (%) | 38 (31.7) | 22 (71.0) | ||||
Hypertension (%) | 39 (32.5) | 3 (9.7) | ||||
CGN (%) | 12 (10.0) | 2 (6.5) | ||||
Others/Unknown (%) | 31 (25.8) | 4 (12.9) | ||||
PD duration (months) | 11.8 ± 21.0 | 11.3 ± 19.0 | 0.909 | |||
D/P Cr at 4-hr PET | 0.61 ± 0.12 | 0.67 ± 0.16 | 0.037 | 0.60 ± 0.11 | 0.66 ± 0.13 | 0.024 |
No. of anti-hypertensive agents | 2.0 ± 1.5 | 2.7 ± 1.6 | 0.025 | 1.3 ± 1.5 | 2.0 ± 1.4 | 0.008 |
Urine output (L/day) | 1.00 ± 0.47 | 1.24 ± 1.71 | 0.444 | 0.83 ± 0.48 | 0.81 ± 0.63 | 0.855 |
Systolic BP (mmHg) | 132.1 ± 25.6 | 139.7 ± 24.8 | 0.143 | 133.6 ± 19.7 | 142.0 ± 25.8 | 0.100 |
Diastolic BP (mmHg) | 79.4 ± 13.2 | 76.2 ± 11.0 | 0.220 | 79.7 ± 10.7 | 77. 8 ± 11.0 | 0.377 |
Pulse pressure (mmHg) | 52.7 ± 19.0 | 63.5 ± 19.3 | 0.006 | 53.9 ± 15.4 | 64.2 ± 18.9 | 0.002 |
Laboratory findings | ||||||
Hemoglobin (g/dL) | 11.1 ± 1.2 | 10.8 ± 1.5 | 0.241 | 11.1 ± 1.6 | 10.3 ± 1.3 | 0.029 |
Glucose (mg/dL) | 122.1 ± 56.7 | 159.4 ± 89.7 | 0.034 | 128.1 ± 70.1 | 153.2 ± 77.6 | 0.084 |
Serum Creatinine (mg/dL) | 8.1 ± 2.7 | 7.5 ± 3.1 | 0.289 | 9.5 ± 3.4 | 9.1 ± 3.3 | 0.471 |
Serum Albumin (g/dL) | 3.7 ± 0.4 | 3.3 ± 0.5 | <0.001 | 3.7 ± 0.4 | 3.4 ± 0.5 | <0.001 |
Echocardiographic parameters | ||||||
LA diameter (mm) | 38.2 ± 6.2 | 40.8 ± 7.2 | 0.052 | 36.7 ± 6.1 | 39.4 ± 6.7 | 0.036 |
LA volume (ml) | 48.3 ± 20.8 | 51.5 ± 19.4 | 0.628 | 45.8 ± 22.9 | 49.4 ± 22.4 | 0.477 |
LVESd (mm) | 32.9 ± 9.7 | 34.1 ± 6.9 | 0.512 | 31.6 ± 10.6 | 34.5 ± 9.4 | 0.165 |
LVEDd (mm) | 50.2 ± 11.1 | 51.1 ± 9.5 | 0.676 | 48.7 ± 11.4 | 50.7 ± 8.5 | 0.359 |
LV mass index (g/m2) | 128.6 ± 69.9 | 140.4 ± 61.9 | 0.395 | 121.1 ± 56.1 | 120.1 ± 46.9 | 0.926 |
ESV (ml) | 38.5 ± 21.7 | 39.0 ± 18.6 | 0.904 | 32.2 ± 15.1 | 37.5 ± 18.6 | 0.107 |
EDV (ml) | 101.8 ± 41.0 | 100.7 ± 35.8 | 0.885 | 83.9 ± 31.7 | 93.7 ± 34.7 | 0.145 |
EF (%) | 62.8 ± 10.1 | 60.0 ± 7.8 | 0.155 | 61.6 ± 6.0 | 58.8 ± 7.9 | 0.034 |
e′ velocity (cm/sec) | 5.7 ± 2.8 | 3.7 ± 2.9 | 0.001 | 5.9 ± 4.7 | 3.7 ± 2.6 | 0.010 |
E/A | 0.88 ± 0.44 | 0.77 ± 0.22 | 0.047 | 0.88 ± 1.2 | 0.67 ± 0.14 | 0.347 |
E/e′ | 11.7 ± 11.1 | 14.9 ± 6.0 | 0.131 | 10.3 ± 4.4 | 13.3 ± 5.0 | 0.004 |