Table 1 Characteristics of patient in the training set and validation set from TANRIC (n = 371).
Variable | Category | Training set | Validation set | ||
|---|---|---|---|---|---|
(n = 187) | % | (n = 184) | % | ||
Age (years) | Median | 60 | 60 | ||
Range (Years) | 19–85 | 28–88 | |||
NA | 0 | 0 | 0 | 0 | |
Sex | Male | 142 | 75.9 | 142 | 77.2 |
NA | 0 | 0 | 0 | 0 | |
Primary site | Larynx | 39 | 20.9 | 42 | 22.8 |
Oral tongue | 52 | 27.8 | 45 | 24.5 | |
Oral cavity | 20 | 10.7 | 18 | 9.8 | |
Others | 76 | 40.6 | 79 | 42.9 | |
NA | 0 | 0 | 0 | 0 | |
Smoking history | Yes | 75 | 40.1 | 79 | 42.9 |
NA | 1 | 0.5 | 2 | 1.1 | |
Alcohol history | Yes | 129 | 69 | 130 | 70.7 |
NA | 3 | 1.6 | 5 | 2.7 | |
History of other malignancy | Yes | 13 | 7.0 | 9 | 4.9 |
NA | 0 | 0 | 0 | 0 | |
History of neoadjuvant treatment | Yes | 2 | 1.1 | 0 | 0 |
NA | 0 | 0 | 0 | 0 | |
Lymph node neck dissection | Yes | 164 | 87.7 | 150 | 81.5 |
NA | 1 | 0.5 | 1 | 0.5 | |
Number of Lymph nodes | ≤45 | 124 | 66.3 | 111 | 60.3 |
>45 | 49 | 26.2 | 46 | 25 | |
NA | 14 | 7.5 | 27 | 14.7 | |
Number of positive LNs | <3 | 130 | 69.5 | 116 | 63 |
≥3 | 42 | 22.5 | 41 | 22.3 | |
NA | 15 | 8.0 | 27 | 14.7 | |
Margin status | Negative | 135 | 72.2 | 143 | 77.7 |
Positive | 32 | 17.1 | 21 | 11.4 | |
NA | 20 | 10.7 | 20 | 10.9 | |
Tumor grade | G1-G2 | 139 | 74.3 | 128 | 69.6 |
G3-G4 | 41 | 21.9 | 55 | 29.9 | |
NA | 7 | 3.7 | 1 | 0.5 | |
Clinical T stage | T1-T2 | 69 | 36.9 | 62 | 33.7 |
T3-T4 | 114 | 61 | 113 | 61.4 | |
NA | 4 | 2.1 | 9 | 4.9 | |
Clinical N stage | N0 | 83 | 44.4 | 90 | 48.9 |
N1-N3 | 97 | 51.9 | 83 | 45.1 | |
NA | 7 | 3.7 | 11 | 6.0 | |
Clinical TNM stage | I-II | 39 | 20.9 | 42 | 22.8 |
III-IV | 145 | 77.5 | 133 | 72.3 | |
NA | 3 | 1.6 | 9 | 4.9 | |
Mutation count | ≤65 | 41 | 21.9 | 37 | 20.1 |
>65 | 146 | 78.1 | 147 | 79.9 | |
NA | 0 | 0 | 0 | 0 | |
Fraction genome altered | ≤ 0.29 | 125 | 66.8 | 126 | 68.5 |
>0.29 | 61 | 32.6 | 55 | 29.9 | |
NA | 1 | 0.5 | 3 | 1.6 | |
