Table 2 Analyses of the associations between serological variables and survival status in 160 critically ill ILD patients.

From: Prognostic effects of clinical and CT imaging features on critically ill patients with interstitial lung disease hospitalized in respiratory intensive care unit

Variables

survivors (n = 58)

nonsurvivors (n = 102)

P value

WBC (*109)

10.0 (7.5–12.0)

10.1 (7.0–13.8)

0.619

N (%)

85.5 (72.6–89.4)

88.3 (80.1–92.3)

0.016

Hb (g/l)

124.5 (107.0–137.3)

125.0 (116.8–142.0)

0.558

PLT (*109)

218.0 (181.3–284.0)

176.5 (121.0–259.3)

0.002

L (*109)

0.97 (0.66–1.39) (n = 53)

0.73 (0.45–1.13) (n = 75)

0.021

CD4+ (*106)

315.5 (186.8–486.5) (n = 54)

189.0 (106.0–368.0) (n = 77)

0.004

CD8+ (*106)

270.5 (148.3–474.3) (n = 54)

183.0 (91.5–388.5) (n = 77)

0.040

PCT (ng/ml)

0.05 (0.02–0.12) (n = 45)

0.08 (0.04–0.27) (n = 66)

0.053

CRP (mg/l)

27.6 (6.9–59.9) (n = 57)

47.8 (9.4–94.6) (n = 101)

0.048

IgA (g/l)

2.6 (1.8–3.3) (n = 53)

2.7 (2.0–3.8) (n = 89)

0.546

IgG (g/l)

12.2 ± 4.2(n = 53)

12.3 ± 4.6(n = 89)

0.960

IgM (g/l)

1.2 (0.9–1.9) (n = 53)

1.0 (0.7–1.4) (n = 89)

0.013

IgE (IU/ml)

102.0 (44.0–222.0) (n = 51)

100.0 (60.0–167.5) (n = 73)

0.974

AST (U/L)

21.3 (15.5–27.2) (n = 57)

27.5 (19.4–45.6) (n = 101)

0.007

ALT (U/L)

22.7 (13.8–36.3) (n = 57)

24.9 (17.2–40.1) (n = 101)

0.212

LDH (U/L)

343.0 (279.0–438.0) (n = 57)

456.0 (310.5–603.0) (n = 101)

0.001

Scr (umol/l)

57.5 (49.8–73.7)

57.0 (46.7–70.2)

0.306

CYF 21-1 (ng/ml)

5.2 (3.9–8.0) (n = 51)

11.0 (7.4–16.6) (n = 89)

0.000

NSE (ng/ml)

15.9 (12.6–22.8) (n = 51)

26.5 (18.7–38.3) (n = 89)

0.000

CEA (ng/ml)

3.1 (2.2–4.2) (n = 51)

6.7 (3.1–12.2) (n = 89)

0.000

PaO2 (mmHg)

74.0 (63.0–89.0) (n = 55)

67.0 (54.8–79.0) (n = 101)

0.014

PaCO2 (mmHg)

37.4 (32.5–43.5) (n = 55)

35.2 (30.6–40.0) (n = 100)

0.106

P/F (mmHg)

230.4 ± 83.1(n = 55)

173.2 ± 79.8(n = 101)

0.000

ANA

29 (54.7%) (n = 53)

34 (37.8%) (n = 90)

0.049

ENA

32 (60.4%) (n = 53)

44 (48.9%) (n = 90)

0.184

ANCA

5 (9.4%) (n = 53)

9 (10.0%) (n = 90)

0.912

G test

4 (8.2%) (n = 49)

19 (27.5%) (n = 69)

0.009

GM test

1 (2.0%) (n = 49)

6 (8.6%) (n = 70)

0.136

  1. Variables: WBC White blood cell count; N Percentage of neutrophil; Hb Hemoglobin; PLT Platelet; L Blood lymphocyte count; CD4 + CD4 + lymphocytes; CD8 + CD8 + lymphocytes; PCT Procalcitonin; CRP C-reactive protein; IgA Immunoglobulin A; IgG Immunoglobulin G; IgM Immunoglobulin M; Ig E Immunoglobulin E; AST Aspartate aminotransferase; ALT Alanine aminotransferase; LDH Lactate dehydrogenase; Scr Serum creatinine; CYF 21-1 Cytokeratin 21-1; NSE Neuron specific enolase; CEA Carcinoembryonic antigen; PaO2 Oxygen partial pressure; PaCO2 Carbon dioxide partial pressure; P/F Oxygenation index; ANA Autoantibody ANA positive; ENA Autoantibody ENA positive; ANCA Anti-neutrophil cytoplasmic antibody positive; G test Fungal glucan test positive; GM test Galactomannan test positive.
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