Figure 8
From: Relaxin reverses maladaptive remodeling of the aged heart through Wnt-signaling
Relaxin blocks fibroblast to myofibroblast transition. Fibroblasts treated with TGFβ showed a marked increase in F-actin (top, n ≥ 53 cells/group) and collagen I (bottom, n ≥ 41 cells/group) expression that was dramatically inhibited by RLX. *Indicates p < 0.05. 400x magnification, scale bars = 25 µm and apply to all panels.
