Table 1 Baseline characteristics according to type of vascular access.

From: The Impact of Comorbidity Burden on The Association between Vascular Access Type and Clinical Outcomes among Elderly Patients Undergoing Hemodialysis

 

Total

(n = 23,100)

Type of vascular access

P

AVF

(n = 14,847)

AVG

(n = 3,906)

CVC

(n = 4,347)

Demographic data

  Age, years

73.7 ± 6.0

73.0 ± 5.7

74.3 ± 5.9

75.9 ± 6.6

<0.001

  Gender, male

12,948 (56.1)

8,672 (58.4)

2,037 (52.2)

2,239 (51.5)

<0.001

  BMI, kg/m2

22.2 ± 4.3

22.3 ± 3.8

21.9 ± 3.2

21.8 ± 6.7

<0.001

  Dialysis vintage, year

3.8 ± 3.3

4.2 ± 3.4

3.7 ± 3.2

2.5 ± 2.6

<0.001

  nPCR, g/kg/day

0.4 ± 0.9

0.4 ± 0.9

0.3 ± 0.6

0.3 ± 0.6

<0.001

  Single-pool Kt/V

1.49 [1.28–1.78]

1.49 [1.28–1.77]

1.53 [1.32–1.79]

1.49 [1.26–1.82]

0.07

  SBP, mmHg

138.9 ± 24.3

138.8 ± 24.9

139.8 ± 24.6

138.2 ± 21.2

0.08

  DBP, mmHg

73.4 ± 16.3

13.6 ± 14.6

72.6 ± 23.9

73.7 ± 12.3

0.03

  Functional status

    

<0.001

   Inability to ambulate

1,508 (11.1)

603 (7.0)

268 (11.1)

637 (24.2)

 

   Need of assistance with daily activities

4,394 (32.3)

2,441 (28.5)

873 (36.3)

1,080 (41.0)

 

   Independently living

7,696 (56.2)

5,514 (64.4)

1,266 (52.6)

916 (34.8)

 

  Etiology of ESRD

    

<0.001

   Diabetic nephropathy

11,804 (51.1)

7,696 (51.8)

2,047 (52.4)

2,061 (47.4)

 

   Hypertension

5,436 (23.5)

3,482 (23.5)

954 (24.4)

1,000 (23.0)

 

   Glomerulonephritis

1,327 (5.7)

920 (6.2)

166 (4.2)

241 (5.5)

 

   Polycystic kidney disease

275 (1.2)

198 (1.3)

44 (1.1)

33 (0.8)

 

   Other

1,329 (5.8)

741 (5.0)

204 (5.2)

384 (8.8)

 

   Unknown

2,929 (12.7)

1,810 (12.2)

491 (12.6)

628 (14.4)

 

  sCCI

5.8 ± 1.1

5.7 ± 1.1

5.9 ± 1.1

6.0 ± 1.2

<0.001

Comorbidities

  Hypertension

11,804 (51.1)

7,696 (51.8)

2,047 (52.4)

2,061 (47.4)

<0.001

  Diabet®es

9,027 (39.1)

5,984 (40.3)

1,604 (41.1)

1,439 (33.1)

<0.001

  Coronary artery disease

3,136 (13.6)

2,077 (14.0)

538 (13.8)

521 (12.0)

0.002

  Congestive heart failure

1,563 (6.8)

968 (6.5)

279 (7.1)

316 (7.3)

0.05

  Cerebrovascular disease

1,428 (6.2)

867 (5.8)

254 (6.5)

307 (7.1)

0.002

  Malignancy

656 (2.8)

413 (2.8)

99 (2.5_

144 (3.3)

0.14

Laboratory findings

  Hemoglobin, g/dL

10.1 ± 3.0

10.2 ± 3.2

10.2 ± 3.2

9.8 0 ± 1.4

<0.001

  Albumin, g/dL

3.8 ± 0.6

3.9 ± 0.6

3.8 ± 0.6

3.5 ± 0.7

<0.001

  Total cholesterol, mg/dL

142.7 ± 39.5

142.5 ± 38.7

142.7 ± 38.9

143.5 ± 42.7

0.55

  HbA1c, %

6.6 ± 7.2

6.7 ± 8.5

6.4 ± 2.5

6.3 ± 4.7

0.19

  Calcium, mg/dL

8.7 ± 0.8

8.7 ± 0.9

8.7 ± 0.8

8.5 ± 0.9

<0.001

  Phosphorous, mg/dL

4.3 ± 1.4

4.4 ± 1.4

4.2 ± 1.4

4.0 ± 1.5

<0.001

  intact-PTH, pg/mL

160.0 ± 148.7

162.6 ± 152.8

150.1 ± 132.4

159.9 ± 148.2

0.001

  1. Data were presented as mean ± standard deviation, median [interquartile range] or number (%).
  2. Abbreviation: AVF, arteriovenous fistula; AVG, arteriovenous graft; CVC, central venous catheter; BMI, body mass index; ESRD, end-stage renal disease; sCCI, simplified Charlson comorbidity index; PTH, parathyroid hormone.