Table 3 The association between type of vascular access and hospitalization at different level of sCCI.

From: The Impact of Comorbidity Burden on The Association between Vascular Access Type and Clinical Outcomes among Elderly Patients Undergoing Hemodialysis

 

Number of hospitalizations†

Access malfunction

Access infection

Mean ± SD

Case (%)†

OR (95% CI)*

P

Case (%)†

OR (95% CI)*

P

Lowest tertile of sCCI (4–5)

 

375 (3.8)

  

57 (0.6)

  

AVF (n = 6,748)

0.6 ± 2.4

184 (2.7)

1.00 (reference)

 

29 (0.4)

1.00 (reference)

 

AVG (n = 1,515)

0.7 ± 1.2

79 (5.2)

1.65 (0.89–3.03)

0.11

15 (1.0)

4.41 (1.35–14.45)

0.01

CVC (n = 1,528)

1.0 ± 1.3

112 (7.3)

2.83 (1.62–4.94)

<0.001

13 (0.9)

1.53 (0.35–6.65)

0.57

Middle tertile of sCCI (6)

 

395 (4.8)

  

57 (0.7)

  

AVF (n = 5,041)

0.8 ± 1.7

181 (3.6)

1.00 (reference)

 

18 (0.40

1.00 (reference)

 

AVG (n = 1,423)

1.0 ± 2.8

74 (5.2)

1.27 (0.80–2.04)

0.31

24 (1.7)

5.00 (1.57–15.90)

0.01

CVC (n = 1,685)

1.2 ± 2.3

140 (8.3)

2.22 (1.41–3.48)

0.001

15 (0.9)

2.74 (0.58–12.85)

0.20

Highest tertile of sCCI (≥7)

 

291 (5.6)

  

66 (1.3)

  

AVF (n = 3,058)

1.1 ± 1.4

120 (3.9)

1.00 (reference)

 

19 (0.6)

1.00 (reference)

 

AVG (n = 968)

1.2 ± 1.3

67 (6.9)

1.74 (1.04–2.92)

0.03

29 (3.0)

3.90 (1.47–10.32)

0.01

CVC (n = 1,134)

1.5 ± 1.4

104 (9.2)

3.76 (2.31–6.11)

<0.001

18 (1.6)

1.27 (0.31–5.22)

0.74

  1. †P for trend < 0.001.
  2. *Models were adjusted for age, sex, dialysis vintage, BMI, predialysis SBP, etiology of ESRD, functional status, history of hypertension, diabetes, or CVDs, hemoglobin, serum albumin, and HbA1c.
  3. Abbreviation: sCCI, simplified Charlson comorbidity index; OR, odds ratio; CI, confidence interval; AVF, arteriovenous fistula; AVG, arteriovenous graft; CVC, central venous catheter; BMI, body mass index; SBP, systolic blood pressure; ESRD, end-stage renal disease; CVD, cardiovascular disease.
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