Figure 5

Titration of a saturated solution of RSV by plain P90G liposomes. ¹H NMR spectra of (a) RSV in D₂O and (b–e) mixtures of RSV with increasing amounts of P90G liposomes (300 K, 500 MHz). * The signal of the solvent is truncated. The sample used to acquire spectrum (a) comprised 600 µL of RSV solution. Spectra (b–e) were recorded after a total addition of 5, 10, 20 and 30 µL of a 100 mg/mL dispersion of plain P90G liposomes. (1) Region showing the signals of RSV (see Fig. 1 for assignment); the signals H-2,6 and H-4 are, respectively, unresolved doublet and triplet with a ⁴J scalar coupling of about 2.2 Hz. (2–3) Regions showing the signals C2, C1 and TMA (trimethylammonium) of the choline head group of P90G; signals G1/G1’ and G3 pertain to the methylene ¹H of the glycerol unit.