Figure 3

Heatmap of miRNA expression profile from array assay of ARPE-19 cells. After 24 h of 600 μM H₂O_2, the miRNA expression profile was analyzed, using an array for microRNA. Hierarchical unsupervised clustering was performed with the expressed miRNAs in ARPE-19 cells. Each column represents an individual cell sample. Orange columns are ARPE-19 cells treat with 600 μM H₂O₂ and green columns ARPE-19 cell controls. Control sample (n = 4) and 600 μM H₂O₂ sample (n = 4). The overexpressed miRNAs are shown in green and under-expressed miRNAs in red. Expression values are calculated with respect to the reference genes of the array assay.