Table 1 Properties of 381 GAS isolated from invasive infections in Portugal during 2010–2015.

From: Changes in emm types and superantigen gene content of Streptococcus pyogenes causing invasive infections in Portugal

emm cluster

(no. of isolates)

emm type

(no. of isolates)

SAg profilea

(no. of isolates)

Antimicrobial resistanceb

(no. of isolates)

A-C3 (105)

1 (105)

3 (11), 10 (93), 44 (1)

S (104), cMLSB (1)

E4 (83)

2 (1)

48 (1)

S (1)

 

22 (9)

21 (1), 40 (1), 53 (4), 91 (1), 95 (1), 103 (1)

S (6), Tet (3)

 

28 (19)

10 (2), 15 (1), 24 (9), 27 (6), 54 (1)

S (15), [cMLSB, Lev, Bac] (2), [cMLSB, Bac] (2)

 

73 (1)

16 (1)

Tet (1)

 

77 (7)

30 (3), 46 (1), 47 (2), 100 (1)

S (2), [iMLSB, Tet] (3), iMLSB (1), Tet (1)

 

84 (1)

9 (1)

S (1)

 

89 (42)

6 (4), 29 (35), 46 (3)

S (39), cMLSB (2), Lev (1)

 

102 (2)

27 (1), 71 (1)

Tet (2)

 

169 (1)

40 (1)

Tet (1)

A-C5 (34)

3 (34)

8 (25), 9 (5), 53 (4)

S (34)

E3 (32)

9 (1)

99 (1)

S (1)

 

44 (9)

32 (4), 38 (3), 56 (1), 97 (1)

S(9)

 

82 (1)

33 (1)

S(1)

 

87 (18)

20 (15), 21 (1), 7 (2)

S (18)

 

103 (1)

40 (1)

Tet (1)

 

118 (2)

29 (1), 44 (1)

Tet (1)

A-C4 (31)

12 (31)

13 (2), 16 (14), 33 (12), 77 (2), 102 (1)

S (30), iMLSB (1)

E6 (28)

11 (4)

16 (1), 29 (2), 46 (1)

S (1), [cMLSB, Tet] (2), Tet (1)

 

75 (19)

25 (13), 28 (2), 42 (2), 45 (1), 64 (1)

S (19)

 

81 (2)

93 (1), 98 (1)

S (2)

 

85 (1)

44 (1)

Tet (1)

 

94 (1)

35 (1)

S (1)

 

99 (1)

46 (1)

Tet (1)

M6 (26)

6 (26)

2 (8), 16 (1), 26 (2), 51 (10), 7 (5)

S (26)

E1 (22)

4 (19)

23 (17), 44 (1), 94 (1)

S (18), Tet (1)

 

78 (2)

29 (2)

S (2)

 

165 (1)

99 (1)

S (1)

E2 (7)

50 (1)

101 (1)

Tet (1)

 

66 (1)

45 (1)

Tet (1)

 

90 (2)

95 (2)

Tet (2)

 

104 (1)

100 (1)

Tet (1)

 

110 (2)

43 (2)

Tet (2)

M5 (6)

5 (6)

29 (6)

S (5), Tet (1)

D4 (4)

33 (1)

67 (1)

Tet (1)

 

43 (1)

96 (1)

S (1)

 

70 (2)

44 (2)

Tet (2)

D2 (1)

71 (1)

10 (1)

S (1)

D3 (1)

123 (1)

29 (1)

S (1)

M18 (1)

18 (1)

4 (1)

S (1)

  1. aThe SAg genes present in each profile are indicated in Supplementary Table S2.
  2. bS, susceptibility to all antimicrobials tested; cMLSB, presenting the cMLSB phenotype of macrolide resistance; iMLSB, presenting the iMLSphenotype of macrolide resistance; Tet, resistance to tetracycline; Lev, nonsusceptibility to levofloxacin; Bac, resistance to bacitracin.