Table 1 Body weight and blood parameter analysis.
Wildtype apoE+/+ rats | Homozygous apoE−/− knockout rats | Heterozygous apoE+/− knockout rats | ||||
|---|---|---|---|---|---|---|
Normal Diet | Western Diet | Normal Diet | Western Diet | Normal Diet | Western Diet | |
Body weight (g) | 530.1 ± 15.94 | 513.6 ± 16.45 | 546.3 ± 28.69 | |||
516.8 ± 11.47 | 539.57 ± 26.46 | 494.0 ± 17.78 | 524.86 ± 23.69 | 497.0 ± 19.04 | 628.3 ± 32.90 | |
TC (mmol/l) | 1.93 ± 0.08 | 5.1 ± 0.78 | 2.9 ± 0.46 | |||
1.94 ± 0.16 | 1.91 ± 0.07 | 6.6 ± 0.61 | 4.46 ± 1.01 | 1.74 ± 0.15 | 4.06 ± 0.52 | |
LDL-C (mmol/l) | 0.35 ± 0.04 | 2.1 ± 0.44 | 0.57 ± 0.14 | |||
0.35 ± 0.06 | 0.36 ± 0.06 | 3.33 ± 0.21 | 1.36 ± 0.41 | 0.26 ± 0.03 | 0.87 ± 0.18 | |
HDL-C (mmol/l) | 1.32 ± 0.13 | 0.67 ± 0.08 | 0.56 ± 0.12 | |||
1.52 ± 0.21 | 1.19 ± 0.13 | 0.68 ± 0.07 | 0.66 ± 0.12 | 0.89 ± 0.09 | 0.23 ± 0.08 | |
TG (mmol/l) | 1.6 ± 0.19 | 3.16 ± 0.50 | 2.97 ± 0.54 | |||
1.50 ± 0.28 | 1.67 ± 0.28 | 2.52 ± 0.67 | 3.44 ± 0.66 | 1.53 ± 0.26 | 4.40 ± 0.44 | |
Glucose (mmol/l) | 15.56 ± 2.02 | 14.61 ± 1.69 | 8.81 ± 0.94 | |||
19.68 ± 3.63 | 12.61 ± 1.77 | 16.53 ± 3.74 | 13.79 ± 1.93 | 10.86 ± 1.16 | 6.76 ± 0.72 | |
Creatinine (μmol/l) | 32.0 ± 1.85 | 31.09 ± 1.20 | 31.8 ± 1.26 | |||
34.4 ± 3.68 | 30.29 ± 1.76 | 34.5 ± 2.02 | 29.14 ± 0.94 | 33.80 ± 1.96 | 29.80 ± 1.16 | |
Uric Acid (μmol/l) | 46.92 ± 2.25 | 42.36 ± 3.13 | 49.6 ± 2.29 | |||
50.2 ± 3.35 | 44.57 ± 2.9 | 39.5 ± 3.57 | 44.0 ± 4.57 | 48.0 ± 3.65 | 51.2 ± 3.01 | |
White Blood Cells (103/μl) | 10.81 ± 1.19 | 9.45 ± 1.03 | 9.32 ± 0.87 | |||
8.88 ± 0.18 | 12.19 ± 1.92 | 8.7 ± 1.41 | 9.87 ± 1.46 | 9.1 ± 1.78 | 9.54 ± 0.48 | |
