Table 2 Viability of C. burnetii after one week culture in ACCM-2 with the indicated antibiotics. A “+” indicates growth on ACCM-2 plates after dilution from the treated culture. A “-” indicates no growth.
From: The Effect of pH on Antibiotic Efficacy against Coxiella burnetii in Axenic Media
pH | [moxifloxacin], μg/ml | ||||
---|---|---|---|---|---|
0 | 0.01 | 0.1 | 1 | 10 | |
4.75 | + | + | + | + | + |
5.25 | + | + | + | + | + |
5.75 | + | + | + | + | + |
6.25 | + | + | + | + | + |
[doxycycline], μg/ml | |||||
pH | 0 | 0.001 | 0.01 | 0.1 | 1 |
4.75 | + | + | + | + | + |
5.25 | + | + | + | + | + |
5.75 | + | + | + | + | + |
6.25 | + | + | + | + | + |
[rifampin], μg/ml | |||||
pH | 0 | 0.001 | 0.01 | 0.1 | 1 |
4.75 | + | + | − | − | − |
5.25 | + | + | − | − | − |
5.75 | + | + | − | + | − |
6.25 | + | + | + | + | + |