Figure 2
From: Participation of 5-lipoxygenase and LTB4 in liver regeneration after partial hepatectomy
Hepatic LTB4 and LTC4 levels detected by ELISA. (a) LTB4 and LTC4 levels in the removed lobes (time zero for surgery and 2 h after zileuton administration). (b) LTB4 and (c) LTC4 hepatic levels at 1, 5 and 24 h post-partial hepatectomy (PH) in animals treated with vehicle or zileuton 40 mg/Kg body weight. Pre-PH: Removed tissue from animals treated with vehicle, Pre-PHZi40: Removed tissue from animals treated with zileuton 40 mg/Kg body weight, Sh: sham animals, PH: partial-hepatectomized animals treated with vehicle, PHZi: PH-animals treated with zileuton 40 mg/Kg body weight. Bars represent mean ± SEM (n = 4 per experimental group). *p < 0.05 vs. Sh or Pre-PH, #p < 0.05 vs. PH for each time.
