Figure 2

Proteomic response to simulated microgravity. (A) PCA of 1618 proteins identified in each of the five replicates in simulated microgravity (blue) and control condition (red). Explanation of the variances in percent of the most influential principal components in brackets. The two most influential loadings for both principal components are included as grey arrows (Uniprot IDs). (B) Gene Ontology clustering of protein classes according to the PANTHER classification tool. Out of the 73 proteins which were identified as more abundant under simulated microgravity, 40 were assigned to protein classes (red). 17 hits were annotated for the 46 less abundant proteins (blue).