Table 2 Differences in analyte concentrations (pg/mL) between Fontan and ASD patients.

From: Angiopoietin-2 predicts morbidity in adults with Fontan physiology

Analyte (pg/mL)

Fontan (n = 6)

ASD (n = 6)

P-Value

Ang-2

7,710.3 ± 2,490.9

1,279.0 ± 637.8

0.000514447*

BMP9

454.0 ± 286.8

359.8 ± 348.6

0.653182

CD44

3,538.7 ± 2317.8

4,006.8 ± 2,614.8

0.772179

E-Selectin

34,278.2 ± 18,351.3

27,824.4 ± 13,118.6

0.54023

EGF

167.5 ± 182.6

129.3 ± 105.2

0.69593

Endostatin

37,581.1 ± 22,718.2

23,190.8 ± 7,085.4

0.213307

FABP4

22,240.5 ± 10,520.7

7,084.5 ± 3,491.6

0.0156468

FGF23

40.8 ± 30.6

11.2 ± 15.5

0.0899409

Gas6

12,481.9 ± 1,928.5

10,038.0 ± 1,721.7

0.0674726

ICAM1

364,736.7 ± 324,691.3

310,227.1 ± 229,749.8

0.767095

MCP-1

114.6 ± 27.3

94.6 ± 26.8

0.276038

MMP1

181.3 ± 99.3

120.9 ± 89.4

0.341724

MMP13

2,093.4 ± 1,229.5

1,863.5 ± 1,462.3

0.794634

MMP3

4,197.9 ± 1,867.9

3,398.9 ± 937.7

0.417549

MMP7

4,874.0 ± 3,775.1

1,212.2 ± 698.6

0.065511

MMP9

11,518.6 ± 2,993.2

10,956.7 ± 2,116.4

0.740628

Tenascin C

9,419.2 ± 1,739.3

7,548.6 ± 1,848.7

0.137993

TIMP1

60,061.3 ± 14,914.8

35,175.4 ± 4,833.5

0.0157517

Thrombospondin-2

59,903.9 ± 20,234.4

19,256.1 ± 16,455.9

0.00825944

vWF

3,418.5 ± 2,896.7

3,220.0 ± 1,781.3

0.899399

  1. Ang-2, angiopoietin-2; BMP9, bone morphogenic protein 9; EGF, epidermal growth factor; FABP4, fatty acid binding protein 4; FGF23, fibroblast growth factor 23; Gas6, growth arrest-specfic protein 6; ICAM1, intracellular adhesion molecule 1; MCP-1, monocyte chemoattractant protein-1; MMP, matrix metalloproteinase; TIMP1, tissue inhibitor of metalloproteinase 1; vWF, von Willebrand factor.
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