Figure 6 | Scientific Reports

Figure 6

From: Ovariectomy increases the incidence and diameter of abdominal aortic aneurysm in a hypoperfusion-induced abdominal aortic aneurysm animal model

Figure 6

Immunohistochemical staining for matrix metalloproteinases (MMPs) and macrophage/monocyte of vascular wall in experiment 2. (A,B,D,E) Representative images of immunostaining for MMP-2 (scale bar = 30 µm). (G,H,J,K) Representative images of immunostaining for MMP-9 (scale bar = 30 µm). (M,N,P,Q) Representative images of immunostaining for macrophage/monocyte (scale bar = 30 µm). Quantification of MMP-2 positive areas of the vascular wall on 3 weeks after OVX (C) and on 7 weeks after OVX (F). Quantification of MMP-9 positive areas of the vascular wall on 3 weeks after OVX (I) and on 7 weeks after OVX (L). Quantification of macrophage/monocyte positive areas of the vascular wall on 3 weeks after OVX (O) and on 7 weeks after OVX (R). (E,K) Control group (n = 8), OVX group (n = 8). (F) Control group (n = 6), OVX group (n = 8). (L,Q) Control group (n = 7), OVX group (n = 9). (R) Control group (n = 7), OVX group (n = 8). *P < 0.05, ***P < 0,001. The arrows show the direction of intima and adventitia. In the case of enlarged figure, all layers of arterial wall were not shown.

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