Figure 6

Stereo drawing of CDR L1 residues of the unliganded isoAsp and normal forms. Hydrogen bonds are shown as broken lines. (A) The structure of the unliganded isoAsp form of 64M-5 Fab is colored yellow. (B) The structure of the unliganded normal form of 64M-5 Fab is colored grey. (C) Superposition of the unliganded isoAsp (yellow) and normal (grey) forms. Side-chain atoms except for isoAsp28L or Asn28L have been omitted for clarity.