Figure 7

Comparison of the ligand-binding sites of 64M-5 Fab (stereo views). (A) The structure of the unliganded isoAsp form is colored yellow, and that of dT(6-4)T-liganded isoAsp form is colored cyan. Water molecules in the dT(6-4)T-liganded form are shown as spheres. Residues of the dT(6-4)T-liganded form are labeled in black, and those of the unliganded form are orange. In the dT(6-4)T-liganded isoAsp form, isoAsp28L is not included in the model. (B) Structures of the dT(6-4)T-liganded isoAsp (cyan) and normal (pink) forms. The residue Asn28L of the normal form is labeled in red.