Figure 2 | Scientific Reports

Figure 2

From: Plasma metabolomics in tuberculosis patients with and without concurrent type 2 diabetes at diagnosis and during antibiotic treatment

Figure 2

TB and TB-DM greatly impact patient plasma metabolite levels. Multiple linear regression models were fitted for each between disease group comparison, and resulting -log-transformed p-values (q-values) are plotted against the regression coefficient estimate for each metabolite: TB vs HC (A), TB-DM vs HC (B), TB-DM vs TB. (C) Each dot represents an individual metabolite. Dot color represents direction and size of the regression coefficient. The significance threshold (q = 0.05) is displayed as a horizontal dotted line. (D) Absolute abundance of individual metabolites per group displayed as Tukey’s boxplots. Significance differences between HC (n = 48), TB (n = 48) and TB-DM (n = 20) groups were determined by Kruskal-Wallis test with post-hoc Dunn’s test. *p = 0.05, **p = 0.01, ***p = 0.001, ****p = 0.0001.

Back to article page