Figure 6 | Scientific Reports

Figure 6

From: Proteasome inhibition disrupts the metabolism of fumarate hydratase- deficient tumors by downregulating p62 and c-Myc

Figure 6

Proteasome inhibition downregulates both glucose and glutamine metabolism. The comparative gene expression of metabolic genes between UOK262 cells treated with each of the three proteasome inhibitors (bortezomib, carfilzomib, or marizomib) and the control DMSO treated UOK262 cells were calculated and represented on a schematic of the major metabolic pathways. B: bortezomib; M: marizomib; C: carfilzomib.

Back to article page