Figure 5 | Scientific Reports

Figure 5

From: Evaluation of binding and inhibition mechanism of dietary phytochemicals with sphingosine kinase 1: Towards targeted anticancer therapy

Figure 5

Interactions of quercetin with SphK1. (A) 2D structural representation of quercetin. The structure of quercetin is composed of three rings (A, B, and C) and five hydroxyl groups. (B) 2D structural representation of SphK1 residues interacting with quercetin. (C) Cartoon representation showing the docked quercetin interacting with the binding site residues of SphK1. (D) Surface potential view of SphK1 binding pocket occupied by quercetin.

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