Table 1 On-off-kinetics of inside-out patch-clamp recordings in TRPM2 species variants.

From: Functional importance of NUDT9H domain and N-terminal ADPR-binding pocket in two species variants of vertebrate TRPM2 channels

 

On-kinetic (τ)

Off-kinetic (τ)

hTRPM2

7.98 ± 1.90 s

8.45 ± 2.02 s

drTRPM2

0.40 ± 0.21 s***

1.42 ± 0.24 s**

nvTRPM2

0.13 ± 0.06 s***

1.46 ± 1.13 s**

  1. Each value represents the mean ± s.d. Statistical significance was assessed using one-way-ANOVA with Bonferroni correction; n = 3. On- and off-kinetics of drTRPM2 and nvTRPM2 were significantly different compared with hTRPM2 but not among each other.
Back to article page