Table 7 Fragment concentrations for titration in protein-observed NMR. The TNKS2 ARC4 concentration was 300 μM.

From: Fragment-based screening identifies molecules targeting the substrate-binding ankyrin repeat domains of tankyrase

[fragment] (μM)

75

150

300

600

1200

2400

4800

ratio fragment:protein

1:4

1:2

1:1

2:1

4:1

8:1

16:1

Back to article page