Figure 5

Representative photographs of the blebs and changes in bleb score after trabeculectomy. (A) Photographs of blebs after treatment with saline, 0.04% MMC, or 10% AMSA 14, 28 and 70 days after surgery. The blebs are visible in the upper right of each image. (B) Changes in bleb score after surgery with saline, 0.04% MMC, and 0.1–10% AMSA. The white circles, black circles, light gray triangles, dark gray diamonds and black squares indicate saline, 0.04% MMC, 0.1% AMSA, 1% AMSA, and 10% AMSA, respectively (n = 5 in each group). The differences among these groups were analyzed with the two-way repeated ANOVA with Bonferroni post-hoc test (P < 0.05 was considered to be statistically significant). The error bar indicates the standard error of the mean. Bars d, e, and f indicate time periods with a significant difference between groups. Bar d: 10% AMSA, 1% AMSA, and 0.04% MMC vs. saline. Bar e: 10% AMSA vs. 0.04% MMC. Bar f: 1% AMSA vs. 0.04% MMC.