Figure 4
Relation between bioluminescence signal and parasite burden measured by limiting dilution. Average radiance (photons/s/cm2/steradian) from liver (A) or spleen (B) ROIs plotted against the matching parasite burden in the corresponding organ. Pooled data of individual mice and from two independent experiments is shown. The dashed line represents the upper limit of the 99% confidence interval of the mean average radiance values obtained for each ROI when applied on images of uninfected BALB/c mice (n = 6). Only animals displaying average radiance levels above the dashed line were considered for the calculation of the Pearson’s correlation coefficients using GraphPad Prism 6.0 version.
