Figure 3

Object Recognition Test in female and male Dusp8 WT and KO mice. (A) Protocol of the object recognition task with three habituation sessions 1–3 followed by a short and a long-term memory test after a 3-hour or 24-hour inter-trial interval (ITI), respectively. (B,C) Interaction times with identical objects in the testing arena for the habituation sessions 1–3 in male (B) and female (C) mice, respectively. (D–G) Short-term memory recognition measures after the 3h-ITI for the familiar and a novel object, shown as total duration spent with the familiar and unfamiliar object, or as object recognition index in male (D,E) or female (F,G) mice. (H–K) depicts the corresponding long-term memory recognition measures after the 24h-ITI with the familiar and a novel unfamiliar object. Male WT: n = 14, male KO: n = 15; female WT: n = 8, female KO: n = 11. Means ± SEM. # p < 0.1; *p < 0.05; **p < 0.01; ***p < 0.001.