Figure 5
From: Dusp8 affects hippocampal size and behavior in mice and humans
Hippocampus weights and volumes in male and female Dusp8 WT and KO mice. Tissue weights were recorded from freshly microdissected hippocampi (A,B). Male WT: n = 7, male KO: n = 6; female WT: n = 7, female KO: n = 7. The knockout of Dusp8 was confirmed in hippocampus lysates using qPCR after RNA extraction. (C,D) H&E stainings of sequential cryosections through the brain (E, scale bar 1 mm) were used to calculate hippocampal volumes of male (F) and female (G) Dusp8 KO and Dusp8 WT mice. Male WT: n = 5, male KO: n = 7, female WT: n = 4, female KO: n = 6. Means ± SEM. **p < 0.01, ***p < 0.001.
