Figure 3
From: A genetic development route analysis on MDS subset carrying initial epigenetic gene mutations

Evolution of initial/driver and last event mutations in 25 paired samples pre and post AML transformation. (a) Distribution of initial/driver and last event mutations for 25 cases at MDS diagnosis. The blue panel represents the mutations that met the criteria for last events; the black panel represents the defined last events mutations according to the criteria described in the text. (b) Distribution of initial/driver and last event mutations for 25 cases after AML transformation. The blue and black panels represent the same mutations described above.