Figure 11

Percentage of eQTLs that are trans-acting at (a) transcript-level and (b) exon-level by chromosomes. Note that these numbers are corresponding to eQTLs that were found at the transcript-level (i.e. includes transcript-only and subset of “both”) and at the exon-level (i.e. includes exon-only and a subset of “both”). Error bars of both plots are model-based standard errors. At the transcript-level (a), the percentage of trans-acting eQTLs clearly varies between chromosomes with some chromosomes having less than 20% of eQTLs being trans-acting (i.e. Chr 5, 9, 13, 16, 17 and 22) while other chromosomes having more than 50% of eQTLs being trans- (i.e. Chr 7, 10, 14, 18, 19 and X). At exon-level (b), the significant interaction of region and chromosome needs to be considered. The error bars are missing for chromosomes 10, 13, 20 and 21 because one or more regions may not have any trans-acting eQTLs (e.g. there are no exon-level trans-acting eQTLs on transcript Chr 20 in the substantia nigra (SNIG).