Figure 7
From: Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes
Network analysis: IPA (QIAGEN Inc., https://www.qiagenbioinformatics.com/products/ingenuity-pathway-analysis)33 network analysis revealed upregulated signaling networks leading to cardiomyocytes death and cardiac fibrosis (A) and suppressed pathways leading to proliferation of cardiomyocytes, autophagy and fibroblast cell death (B). Exosome treatment of LPS stimulated cells upregulated signaling networks leading to increased cell viability and cell survival (C) while it decreased apoptotic signaling network (D).
