Table 5 Multivariable logistic regression analysis for the presence of MCI (adjusted by enterotype III).

From: The relationship between the gut microbiome and mild cognitive impairment in patients without dementia: a cross-sectional study conducted in Japan

 

OR

95% CI

P

Model 1

Age, years*

3.46

1.58–8.97

0.001

Female sex

0. 82

0.22–2.95

0.766

Education, years

0.83

0.37–1.85

0.643

ApoE ε4 carrier*

13.4

2.08–156.3

0.004

Enterotype III*

0.09

0.02–0.42

0.002

F/B ratio

1.37

0.94–2.34

0.115

Model 2

Age, years*

3.68

1.80–8.81

<0.001

ApoE ε4 carrier*

9.65

1.63–100.3

0.01

Enterotype III*

0.19

0.05–0.65

0.008

Model 3

Age, years*

3.68

1.80–8.81

<0.001

ApoE ε4 carrier*

9.65

1.63–100.3

0.010

Enterotype III*

0.19

0.05–0.65

0.008

  1. Abbreviations: CI, confidence interval; OR, odds ratio; ApoE, apolipoprotein E; F/B ratio, Firmicutes/Bacteroidetes ratio; WMH, white matter hyperintensity; CMB, cerebral microbleeds.
  2. The asterisk indicates statistical significance.
  3. Models 1–3 were adjusted using the same formula in Table 4.