Table 2 Overview of the tested substances including information on BBB permeability and manufacturer.
Active substance | BBB Permeability | Formulation | Manufacturer | |
|---|---|---|---|---|
Ampicillin | − | Unasyan | Pfizer | |
Aspirin | − | Aspro | MCM Klosterfrau | |
Cetirizine | − | Cetiristad | Stada | |
Cimetidine | − | Ulcostad | Stada | |
Domperidone | − | Motilium | Janssen | |
Fexofenadine | − | Allegra | Sanofi | |
Fluvastatin | − | Fluvastatin | Stada | |
Furosemide | − | Furohexal | Hexal | |
Loperamide | − | Enterobene | Ratiopharm | |
Loratadine | − | Loratadin Alternova | Krka | |
Mannitol | − | Mannitol | BDA microanalytical reagents | |
Penicillin G | − | Penicillin-G Natrium | Sandoz | |
Verapamil | − | Verabene | Ratiopharm | |
Alprazolam | + | Alprazolam | Ratiopharm | |
Amitriptyline | + | Saroten | Lundbeck | |
Atenolol | + | Atenolol | 1A Pharma | |
Bisoprolol | + | Bisoprolol | Sandoz | |
Caffeine | + | Coffekapton | Strallhofer Pharma GmbH | |
Clomipramine | + | Anafranil | Novartis | |
Clonidine | + | Catapresan | Boehringer Ingelheim | |
Dehydrocortisol | + | Prednisolon | Takeda | |
Desloratadine | + | Desloratadine | Genericon Pharma | |
Diazepam | + | Gewalcam | Takeda | |
Dronabinol | + | Dronabinol | Bionorica | |
Estradiol | + | Estradiol | Sigma Aldrich | |
Fluoxetine | + | Mutan | Gerot Lannach | |
Haloperidol | + | Haldol | Janssen | |
Hydroxyzine | + | Atarax | UCB Pharma | |
Ibuprofen | + | Ibuprofen | Genericon Pharma | |
Lidocaine | + | Lidocain | Apotheke | |
Lovastatine | + | Lovastatine | KRKA | |
Mefloquine | + | Lariam | Roche | |
Metoprolol | + | Metoprolol Genericon | Genericon Pharma | |
Morphine | + | Morapid | Mundi Pharma | |
Naltrexone | + | Dependex | Amomed | |
Nebivolol | + | Nomexor | A. Menarini Pharma GmbH | |
Oxacepam | + | Praxiten | Meda | |
Paracetamol | + | Paracetamol | Genericon Pharma | |
Piracetam | + | Cerebryl | Kwizda Pharma | |
Propanolol | + | Inderal | Astra Zeneca | |
Quetiapine | + | Seroquel | Astra Zeneca | |
Ranitidine | + | Ranic | Hexal | |
Salbutamol | + | Sultanol | GSK Pharma GmbH | |
Sertraline | + | Sertraline | 1 A Pharma | |
Simvastatin | + | Simvastatin | +pharma | |
Sumatriptan | + | Sumatriptan | 1 A Pharma | |
