Figure 1
From: A genome-scale CRISPR/Cas9 knockout screening reveals SH3D21 as a sensitizer for gemcitabine
Essential gene sets for Panc1 cells survival. (a) Overview of the screening. (b) Comparing the read counts of the sgRNAs from day 7 and day 22 baseline samples. (c) Gene set enrichment analysis using sgRNAs’ read count of day 22 and day 7 baseline samples. Gene Ontology (GO) All gene sets were employed for the analysis with minimum size of 20 and maximum size of 200 for gene sets. (d) GSEA using Hallmark All gene sets with minimum size of 20 and maximum size of 200 employing sgRNAs’ read count from day 22 and day 7 baseline samples. Red line indicates rank at max. Left to the red line is leading subset.
