Figure 3
From: Patterns of diverse gene functions in genomic neighborhoods predict gene function and phenotype
The gene function profile of genomic neighborhoods enables a more accurate methodology to infer gene function. The distribution of area under the precision-recall curve (AUPRC) scores, measured in cross-validation, for all examined gene functions (GO terms) is represented in prokaryotes (top), fungi (middle) and metazoa (bottom). The methods compared are the nearest neighbor (NN) classifiers (1-NN, 3-NN, 10-NN), a network-based approach (Gaussian Field Label Propagation, GFP) and finally the novel Neighbourhood Function Profile (NFP) method. See Supplementary 1, Figures S17, S20 and S23 for the area under ROC curve (AUC) scores. P-values are from a one-tailed Wilcoxon signed-rank test.
