Table 1 Bone mineral density and bone microstructure of each group at postoperative 2 weeks.

From: Experimental arthritis and Porphyromonas gingivalis administration synergistically decrease bone regeneration in femoral cortical defects

parameter

(unit)

Group W; CIA(−) P.g(−)

Group P; CIA(−) P.g(+)

Group C; CIA(+) P.g(−)

Group PC; CIA(+) P.g(+)

TV

(mm3)

1.13 ± 0.07

1.09 ± 0.07

1.20 ± 0.04

1.24 ± 0.03

BV

(mm3)

0.14 ± 0.01

0.12 ± 0.01

0.11 ± 0.01

0.11 ± 0.01

BV/TV

(%)

12.8 ± 1.0

11.3 ± 0.94

8.98 ± 0.70

9.15 ± 0.57*

Tb.Th

(µm)

62.5 ± 4.36

55.0 ± 3.29

55.1 ± 1.84

51.1 ± 4.28

Tb.N

(1/mm)

1.29 ± 0.05

1.34 ± 0.07

1.15 ± 0.07

1.20 ± 0.08

Tb.Sp

(µm)

157 ± 7.59

156 ± 9.14

178 ± 6.49

179 ± 6.98

Tb.Spac

(µm)

220 ± 6.07

211 ± 7.65

233 ± 6.22

230 ± 8.54

TMD

(mg/cm3)

643 ± 32.6

524 ± 16.9*

500 ± 17.0**

506 ± 35.2*

vBMD

(mg/cm3)

80.9 ± 5.52

59.3 ± 4.97

44.7 ± 3.6**

41.5 ± 4.04**

  1. Data are expressed as mean ± SEM, n = 6–8/group. CIA(+) or (−); with or without collagen-induced arthritis, P.g(+) or (−); with or without P. gingivalis administration, TV; tissue volume, BV; bone volume, Tb.Th; trabecular thickness, Tb.N; trabecular number, Tb.sp; trabecular separation, Tb.spac; trabecular spacing, TMD; tissue mineral density, vBMD; volumetric bone mineral density, *P < 0.05, **P < 0.01 compared with the group W.