Figure 8
From: In Vivo Activity of Amodiaquine against Ebola Virus Infection
Comparison of desethylamodiaquine concentrations in healthy and EBOV-infected animals. DEAQ plasma concentrations of healthy subjects (black) from the pharmacokinetics study were compared with samples of infected animals in group 2 (treatment on days 0, 1, 2 postexposure; blue) at 24 h after the 3rd dose (a), group 3 (treatment on days 3, 4, 5 postexposure; red) at 0 h after the 3rd treatment (b), or group 3 at 48 h after the 3rd treatment (c). DEAQ concentrations are shown as mean ± SD (d). DEAQ concentrations were adjusted for the dilution factor 5.5.
