Table 3 Top diseases and functions of significant differentially expressed genes in treated vs. untreated GBM tissue.
Diseases and disorders | p-value | molecules of 2527 in total |
---|---|---|
Cancer | 6.38 × 10−04 − 1.00 × 10−63 | 2306 |
- Tumorigenesis of tissue | 1.29 × 10−62 | 2189 |
- Malignant solid tumor | 4.32 × 10−58 | 2263 |
- Glioma | 5.59 × 10−04 | 216 |
Organismal injury and abnormalities | 6.38 × 10−04 − 1.00 × 10−63 | 2327 |
Gastrointestinal disease | 4.31 × 10−04 − 2.00 × 10−56 | 2148 |
Hepatic system disease | 4.31 × 10−04 − 2.09 × 10−39 | 1632 |
Reproductive system disease | 1.93 × 10−04 − 2.98 × 10−36 | 1514 |
Molecular and cellular functions | ||
Gene expression | 5.07 × 10−08 − 6.05 × 10−13 | 514 |
Cellular assembly and maintenance | 6.38 × 10−04 − 1.13 × 10−12 | 525 |
Cellular function and maintenance | 3.19 × 10−04 − 1.13 × 10−12 | 406 |
Cell death and survival | 6.22 × 10−04 − 1.36 × 10−10 | 778 |
Cell cycle | 5.47 × 10−04 − 5.51 × 10−10 | 348 |
- Cell cycle progression | 5.51 × 10−10 | 251 |
- Proliferation of tumor cells | 6.38 × 10−04 | 99 |
Physiological system development | ||
Organismal survival | 9.88 × 10−13 − 1.30 × 10−13 | 554 |
Nervous system development and function | 5.53 × 10−04 − 9.90 × 10−12 | 380 |
Tissue morphology | 5.53 × 10−04 − 1.18 × 10−09 | 268 |
Organ morphology | 4.31 × 10−04 − 1.10 × 10−08 | 255 |
Organismal development | 4.35 × 10−04 − 1.10 × 10−08 | 551 |