Table 2 Cox proportional hazards regression analysis of factors associated with graft failure in living donor liver transplantation recipients.

From: Early postoperative weight gain is associated with increased risk of graft failure in living donor liver transplant recipients

 

Unadjusted

Multivariable adjusteda

HR

95% CI

P-value

HR

95% CI

P-value

Age (years)

1.034

1.011

1.058

0.003

1.028

1.006

1.050

0.013

Sex, male

0.641

0.452

0.909

0.013

    

Body mass index (kg/m2)

1.008

0.958

1.061

0.752

    

Diabetes mellitus

1.325

0.911

1.927

0.142

    

Hypertension

0.718

0.414

1.247

0.239

    

Coronary arterial disease

0.591

0.188

1.854

0.367

    

Fulminant hepatic failure

2.242

1.241

4.050

0.007

2.526

1.344

4.744

0.004

Model for end-stage liver disease score

1.037

1.017

1.057

<0.001

    

Hepatic encephalopathy

1.844

1.238

2.746

0.003

    

Ascites

1.397

0.994

1.963

0.054

    

Spontaneous bacterial peritonitis

1.343

0.706

2.554

0.369

    

Combined hepatocellular carcinoma

0.931

0.670

1.293

0.669

    

Brain natriuretic peptide (pg/mL)

1.001

1.001

1.002

<0.001

1.001

1.001

1.002

<0.001

Donor age (years)

1.029

1.011

1.049

0.002

1.021

1.001

1.042

0.041

Donor sex, male

0.997

0.692

1.438

0.989

    

Donor body mass index (kg/m2)

1.042

0.984

1.102

0.156

    

Total fatty change (%)

1.019

0.995

1.043

0.119

    

Macro fatty change (%)

1.024

0.990

1.059

0.172

    

Graft-to-recipient weight ratio

1.650

0.884

3.079

0.116

    

Postreperfusion syndrome

1.587

1.142

2.206

0.006

    

Cold ischaemic time (min)

1.000

0.997

1.003

0.973

    

Warm ischaemic time (min)

1.001

0.997

1.005

0.547

    

Operation time (h)

1.082

1.014

1.154

0.017

    

Packed red blood cell transfusion (units)

1.019

1.012

1.026

<0.001

1.015

1.007

1.023

<0.001

Epinephrine use

1.585

1.141

2.204

0.006

    

Vasopressor use

1.088

0.777

1.523

0.623

    

Postoperative weight gain ≥3%

2.047

1.462

2.867

<0.001

1.763

1.248

2.490

0.001

  1. HR, hazard ratio; CI, confidence interval. aAdjusted for all variables in the table.