Table 2 Cox proportional hazards regression analysis of factors associated with graft failure in living donor liver transplantation recipients.
Unadjusted | Multivariable adjusteda | |||||||
---|---|---|---|---|---|---|---|---|
HR | 95% CI | P-value | HR | 95% CI | P-value | |||
Age (years) | 1.034 | 1.011 | 1.058 | 0.003 | 1.028 | 1.006 | 1.050 | 0.013 |
Sex, male | 0.641 | 0.452 | 0.909 | 0.013 | ||||
Body mass index (kg/m2) | 1.008 | 0.958 | 1.061 | 0.752 | ||||
Diabetes mellitus | 1.325 | 0.911 | 1.927 | 0.142 | ||||
Hypertension | 0.718 | 0.414 | 1.247 | 0.239 | ||||
Coronary arterial disease | 0.591 | 0.188 | 1.854 | 0.367 | ||||
Fulminant hepatic failure | 2.242 | 1.241 | 4.050 | 0.007 | 2.526 | 1.344 | 4.744 | 0.004 |
Model for end-stage liver disease score | 1.037 | 1.017 | 1.057 | <0.001 | ||||
Hepatic encephalopathy | 1.844 | 1.238 | 2.746 | 0.003 | ||||
Ascites | 1.397 | 0.994 | 1.963 | 0.054 | ||||
Spontaneous bacterial peritonitis | 1.343 | 0.706 | 2.554 | 0.369 | ||||
Combined hepatocellular carcinoma | 0.931 | 0.670 | 1.293 | 0.669 | ||||
Brain natriuretic peptide (pg/mL) | 1.001 | 1.001 | 1.002 | <0.001 | 1.001 | 1.001 | 1.002 | <0.001 |
Donor age (years) | 1.029 | 1.011 | 1.049 | 0.002 | 1.021 | 1.001 | 1.042 | 0.041 |
Donor sex, male | 0.997 | 0.692 | 1.438 | 0.989 | ||||
Donor body mass index (kg/m2) | 1.042 | 0.984 | 1.102 | 0.156 | ||||
Total fatty change (%) | 1.019 | 0.995 | 1.043 | 0.119 | ||||
Macro fatty change (%) | 1.024 | 0.990 | 1.059 | 0.172 | ||||
Graft-to-recipient weight ratio | 1.650 | 0.884 | 3.079 | 0.116 | ||||
Postreperfusion syndrome | 1.587 | 1.142 | 2.206 | 0.006 | ||||
Cold ischaemic time (min) | 1.000 | 0.997 | 1.003 | 0.973 | ||||
Warm ischaemic time (min) | 1.001 | 0.997 | 1.005 | 0.547 | ||||
Operation time (h) | 1.082 | 1.014 | 1.154 | 0.017 | ||||
Packed red blood cell transfusion (units) | 1.019 | 1.012 | 1.026 | <0.001 | 1.015 | 1.007 | 1.023 | <0.001 |
Epinephrine use | 1.585 | 1.141 | 2.204 | 0.006 | ||||
Vasopressor use | 1.088 | 0.777 | 1.523 | 0.623 | ||||
Postoperative weight gain ≥3% | 2.047 | 1.462 | 2.867 | <0.001 | 1.763 | 1.248 | 2.490 | 0.001 |