Figure 2
From: Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor
Sexually dimorphic dyslipidemia, hepatic injury, and steatosis in CAR−/− mice. Plasma Cholesterol, Triglyceride, Free Fatty Acid (A), ALT and AST levels (B), Histological sections of liver stained with H&E, magnification × 100 and steatosis and inflammatory score (C) and hepatic neutral lipid levels (TG: triglycerides; CE: cholesterol esters) (D) in WT and CAR−/− male and female mice aged 68 weeks. Data are presented as mean ± s.e.m. *p < 0.05, ***p < 0.001, n = 18 per group. ALT: alanine transaminase; AST: aspartate transaminase; FFA: free fatty acid; LDL: low-density lipoprotein; HDL: high-density lipoprotein.
