Table 2 Comparisons of levels of glucolipid metabolism biomarkers and sleep parameters between preoperative and postoperative.

From: Association between Upper-airway Surgery and Ameliorative Risk Markers of Endothelial Function in Obstructive Sleep Apnea

Variables

Preoperative

Postoperative

Mean Change (95% CI)

p value

Anthropometric data

BMI (Kg/m2)

27.53 ± 2.55

27.95 ± 2.88

−0.68 (−1.13, −0.23)

0.376

WC (cm)

98.05 ± 7.50

98.10 ± 7.75

−0.64 (−2.24, 0.97)

0.841

SBP (mmHg)

124.00 (122.55, 130.13)

121.00 (120.73, 130.45)

−1.20 (−5.02, 2.61)

0.657

DBP (mmHg)

85.00 (81.50, 87.72)

80.00 (78.36, 85.91)

−3.16 (−5.73, −0.59)

0.087

Glycometabolism indices

Fasting glucose (mmol/L)

5.35 (5.17, 5.95)

5.19 (4.94, 5.45)

−0.36 (−0.72, −0.01)

0.034*

HOMA-IR

3.63 ± 2.06

2.77 ± 1.35

−0.84 (−1.55, −0.13)

0.009*

Lipid metabolism indices

TC (mmol/L)

5.09 ± 0.99

4.48 ± 0.76

−0.61 (−0.86, −0.36)

<0.001**

TG (mmol/L)

1.80 (1.72, 2.81)

1.89 (1.62, 2.11)

−0.40 (−0.87, 0.07)

0.232

HDL-C (mmol/L)

1.08 ± 0.23

1.05 ± 0.18

−0.03 (−0.09, 0.04)

0.432

LDL-C (mmol/L)

3.33 ± 0.83

2.95 ± 0.69

−0.37 (−0.60, −0.15)

0.002*

Apo A (g/L)

1.09 (1.04, 1.14)

1.06 (1.05, 1.18)

0.03 (−0.04, 0.09)

0.53

Apo B (g/L)

0.91 ± 0.18

0.77 ± 0.16

−0.13 (−0.18, −0.08)

<0.001**

Sleep data

AHI

53.95 (49.65, 61.92)

20.35 (18.74, 30.31)

−31.26 (−37.16, −25.35)

<0.001**

Mean SaO2 (%)

92.20 (90.96, 93.08)

95.00 (94.15, 95.33)

2.72 (1.73, 3.71)

<0.001**

LSpO2 (%)

73.47 ± 9.77

82.34 ± 8.34

8.87 (5.82, 11.92)

<0.001**

CT90 (%)

21.78 (18.29, 30.06)

2.44 (3.63, 11.23)

−16.75 (−21.93, −11.57)

<0.001**

ODI

55.26 ± 19.63

27.50 ± 20.33

−27.77 (−33.92, −21.61)

<0.001**

MAI

40.03 ± 26.70

29.05 ± 17.67

−10.98 (−18.98, −2.99)

0.008*

ESS

10.30 ± 5.61

6.59 ± 5.06

−3.45 (−5.10, −1.81)

<0.001**

  1. Abbreviations: BMI = body mass index, WC = waist circumference, SBP = systolic blood pressure, DBP = diastolic blood pressure, HOMA-IR = homeostasis model of assessment for insulin resistance index, TC = total cholesterol, TG = total triglycerides, HDL-C = high-density lipoprotein cholesterol, LDL-C = low-density lipoprotein cholesterol, Apo A = apolipoprotein A, Apo B = apolipoprotein B, AHI = apnea-hypopnea index, SaO2 = oxygen saturation, LSpO2 = lowest pulse oxygen saturation, CT90 = percentage of time during which oxyhemoglobin saturation was < 90%, ODI = oxygen desaturation index, MAI = micro-arousal index, ESS = Epworth Sleepiness Scale, CI = confidence interval.
  2. *p < 0.05; **p < 0.001.
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