Table 6 Multivariable linear regression analyses with changes in serum levels of 10 markers, PSG parameters and biomarker levels.

	ΔAHI	ΔMean SaO₂	ΔLSpO₂	ΔCT90%	ΔODI	ΔMAI	ΔESS	ΔGlucose	ΔHOMA-IR	ΔTC	ΔLDL-C	ΔApoB
ΔVEGFA	0.001	6.334	0.423	1.071*	0.142	−0.131	−0.817	13.406*	−1.859	9.299	−25	−52.019
ΔAng2	−0.004	−0.009	−0.007	−0.007*	0.008*	−0.003	0.014	−0.069*	0.009	−0.013	0.033	0.896*
ΔE-selectin	0.02	0.23	−0.41	−2.649	5.112	−0.008	0.319	39.159	−9.695	−0.886	−4.8	101.277
ΔvWF	1.073	−11.994	−3.123	−5.123	0.399	−0.669	2.951	−9.962	−9.847	45.051	−4.8	−260.24
ΔvWFCP	−4.076	−8.073	−0.41	−2.649	5.112	−0.008	0.319	39.159	−9.695	−0.886	−30.332	101.277
ΔTM	0.001	0.01	0.003	0.005	−0.001	0	−0.001	−0.005	−0.006	0.038	−0.001	−0.087

Abbreviations: VEGFA = vascular endothelium growth factor A, Ang2 = angiopoietin-2, E-selectin = endothelial-leukocyte adhesion molecule, vWF = von willebrand factor, vWFCP = von willebrand factor cleavage protease, TM = thrombomodulin, AHI = apnea-hypopnea index, SaO₂ = oxygen saturation, LSpO₂ = lowest pulse oxygen saturation, CT90 = percentage of time during which oxyhemoglobin saturation was < 90%, ODI = oxygen desaturation index, MAI = micro-arousal index, ESS = Epworth Sleepiness Scale, HOMA-IR = homeostasis model of assessment for insulin resistance index, TC = total cholesterol, LDL-C = low-density lipoprotein cholesterol, Apo B = apolipoprotein B.
*p < 0.05.

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