Table 1 Characteristics of IgAN and chronic tonsillitis (control) groups.

From: Specific strains of Streptococcus mutans, a pathogen of dental caries, in the tonsils, are associated with IgA nephropathy

Years

IgAN group (n = 61)

Control group (n = 40)

p-value

Age (year; mean ± SD)

35.9 (32.9–38.9)

30.3 (27.4–33.2)

0.0359

Sex (M/F)

31/30

28/12

0.0655

Cnm-positive area/total tonsillar area ratio (mean ± SD)

0.32 ± 0.17

0.04 ± 0.06

<0.0001

Positive rate of Cnm-positive S. mutans in tonsils (%)

24.5

0.0

0.0003

Serum creatinine (mg/dL; mean ± SD)

0.8 ± 0.2

0.7 ± 0.1

0.4764

eGFR (mL/min; mean ± SD)

83.4 ± 19.5

90.9 ± 12.9

0.0658

% of urinary protein 1 + or higher

78.6

2.5

<0.0001

% of urinary occult blood 1 + or higher

95.0

4.7

<0.0001

  1. SD: standard deviation, eGFR: estimated glomerular filtration rate
  2. Bold values indicate statistical significance at p < 0.05.
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