Figure 2

ASCcm activates mTOR/PPARγ signaling in macrophage. Expression of phospo-AKT, phospo-mTOR and arginase-1 by macrophage exposed to ASCcm was analyzed by western blot (A) and densitometric data (B) for each time point are shown. In (C), Immunoblot and densitometric data show increased expression of PPARγ in macrophages exposed to ASCcm for 24 h. The images are representative of at least three different blots and β-actin Data are expressed as mean ± SEM of three independent experiments. *p < 0.05 versus CTRL.