Figure 8
From: In silico analysis of alternative splicing on drug-target gene interactions
Summary of isoform specificity of different drugs. (a) Pie chart showing percentages of the 4 types. Type I: targets ≥2 isoforms when at least one is downregulated; Type II: ignores at least one upregulated isoform in cancer; Type III: both Type I and II. (b) Venn diagram showing counts of Type I, Type II and Type III (overlap of Type I and II). Type I: targets ≥2 isoforms when at least one is downregulated; Type II: ignores at least one upregulated isoform in cancer; Type III: both Type I and II.
