Figure 2

Influence of rolipram on pro-inflammatory cytokines in serum of mice challenged with LPS. Mice received vehicle or rolipram (10 mg/kg i.p.) 1 hr before LPS (15 mg/kg i.p.) injection. Blood samples were collected at 0, 3, 12, 24, and 48 hr after LPS injection for cytokine/chemokine assays. Data was collected from 5 mice in each group and was represent the mean and SD. Comparisons between two groups were performed using two-tailed unpaired Student’s T-tests. *Represents p < 0.05 vs. control, #represents p < 0.05 vs. LPS alone.