Table 1 Maternal characteristics according to glucocorticoid treatment during pregnancy in the Puberty Cohort.
From: In Utero Exposure to Glucocorticoids and Pubertal Timing in Sons and Daughters
Glucocorticoids in pregnancy | None | ICS1/INCS12 | Other3 | Total |
|---|---|---|---|---|
n (%) | 14691 (93.2) | 493 (3.1) | 585 (3.7) | 15769 (100.0) |
Pre-pregnancy BMI4, mean (sd) | 23.8 (4.5) | 24.5 (5.1) | 24.2 (4.9) | 23.8 (4.6) |
Missings, n (%) | 195 (1.3) | 10 (2.0) | 10 (1.7) | 215 (1.4) |
Maternal age at delivery in years, mean (sd) | 30.6 (4.4) | 31.1 (4.6) | 31.0 (4.3) | 30.6 (4.4) |
Missings, n (%) | 6 (0.04) | 0 (0.0) | 0 (0.0) | 6 (0.04) |
Maternal age of menarche, n (%) | ||||
Earlier than peers, n (%) | 3681 (25.1) | 142 (28.8) | 166 (28.4) | 3989 (25.3) |
Same time as peers, n (%) | 8379 (57.0) | 260 (52.7) | 330 (56.4) | 8969 (56.9) |
Later than peers, n (%) | 2514 (17.1) | 87 (17.7) | 88 (15.0) | 2689 (17.1) |
Missings, n (%) | 117 (0.8) | 4 (0.8) | 1 (0.2) | 122 (0.8) |
Daily number of cigarettes in 1st trimester, n (%) | ||||
Non-smoker, n (%) | 10479 (71.3) | 396 (80.3) | 434 (74.2) | 11309 (71.7) |
−10 cigarettes/day, n (%) | 3304 (22.5) | 72 (14.6) | 125 (21.4) | 3501 (22.2) |
>10 cigarettes/day, n (%) | 857 (5.8) | 23 (4.7) | 26 (4.4) | 906 (5.8) |
Missings, n (%) | 51 (0.4) | 2 (0.4) | 0 (0.0) | 53 (0.3) |
Alcohol units per week in 1st trimester, n (%) | ||||
0 units, n (%) | 7599 (51.7) | 259 (52.5) | 274 (46.8) | 8132 (51.6) |
>0–1 units, n (%) | 4576 (31.2) | 145 (29.4) | 192 (32.8) | 4913 (31.2) |
>1–3 units, n (%) | 1743 (11.9) | 62 (12.6) | 94 (16.1) | 1899 (12.0) |
>3 units, n (%) | 752 (5.1) | 26 (5.3) | 25 (4.3) | 803 (5.1) |
Missings, n (%) | 21 (0.1) | 1 (0.2) | 0 (0.0) | 22 (0.1) |
Highest social class of parents, n (%) | ||||
High grade professional, n (%) | 3360 (22.9) | 141 (28.6) | 175 (29.9) | 3676 (23.3) |
Low grade professional, n (%) | 4823 (32.8) | 161 (32.7) | 192 (32.8) | 5176 (32.8) |
Skilled worker, n (%) | 4111 (28.0) | 110 (22.3) | 127 (21.7) | 4348 (27.6) |
Unskilled worker, n (%) | 2003 (13.6) | 63 (12.8) | 71 (12.1) | 2137 (13.6) |
Student, n (%) | 284 (1.9) | 10 (2.0) | 16 (2.7) | 310 (2.0) |
Economically inactive, n (%) | 81 (0.6) | 6 (1.2) | 4 (0.7) | 91 (0.6) |
Missings, n (%) | 29 (0.2) | 2 (0.4) | 0 (0.0) | 31 (0.2) |
Asthma in pregnancy, n (%) | ||||
No, n (%) | 14059 (95.7) | 176 (35.7) | 518 (88.6) | 14753 (93.6) |
Yes, n (%) | 628 (4.3) | 317 (64.3) | 67 (11.5) | 1012 (6.4) |
Missings, n (%) | 4 (0.03) | 0 (0.0) | 0 (0.0) | 4 (0.03) |
Allergy in pregnancy, n (%) | ||||
No, n (%) | 12957 (88.2) | 163 (33.1) | 306 (52.3) | 13426 (85.1) |
Yes, n (%) | 1692 (11.5) | 328 (66.5) | 277 (47.4) | 2297 (14.6) |
Missings, n (%) | 42 (0.3) | 2 (0.4) | 2 (0.3) | 46 (0.3) |
Skin disease in pregnancy, n (%) | ||||
No, n (%) | 13889 (94.5) | 431 (87.4) | 315 (53.9) | 14635 (92.8) |
Yes, n (%) | 749 (5.1) | 59 (12.0) | 267 (45.6) | 1075 (6.8) |
Missings, n (%) | 53 (0.4) | 3 (0.6) | 3 (0.5) | 59 (0.4) |
Muscle or joint disease in pregnancy, n (%) | ||||
No, n (%) | 13000 (88.5) | 422 (85.6) | 494 (84.4) | 13916 (88.3) |
Yes, n (%) | 1649 (11.2) | 67 (13.6) | 91 (15.6) | 1807 (11.5) |
Missings, n (%) | 42 (0.3) | 4 (0.8) | 0 (0.0) | 46 (0.3) |
