Table 2 Correlation between AAT-A3F and clinicopathological parameters.

From: Tri-antennary tri-sialylated mono-fucosylated glycan of alpha-1 antitrypsin as a non-invasive biomarker for non-alcoholic steatohepatitis: a novel glycobiomarker for non-alcoholic steatohepatitis

 

r

P value

Age (Yr)

0.092

NS

BMI (kg/m2)

0.066

NS

Plt (104/μL)

−0.172

NS

Albumin (g/dL)

−0.252

<0.001

T-bil (mg/dL)

0.071

NS

AST (IU/L)

0.196

NS

ALT (IU/L)

−0.019

NS

ChE (U/L)

−0.284

<0.001

γ-GTP (IU/L)

0.165

NS

AFP (ng/mL)

0.188

NS

TG (mg/dL)

−0.113

<0.05

LDL-C (mg/dL)

0.087

NS

HDL-C (mg/dL)

−0.136

NS

HbA1c (%)

0.035

NS

FBS (mg/dL)

0.009

NS

IRI (μIU/L)

0.178

NS

HOMA-IR

0.130

NS

cCK18 (U/L)

0.121

NS

M2BPGi (COI)

0.415

<0.001

FIB4 index

0.268

<0.01

APRI

0.236

NS

Pathological findings

Steatosis (0/1/2/3)

−0.012

NS

Lobular inflammation (0/1/2/3)

0.314

<0.01

Ballooning (0/1/2)

0.285

<0.01

Fibrosis (0/1/2/3/4)

0.292

<0.001

  1. The relationship between AAT-A3F and clinicopathological parameters was analysed using Spearman’s R correlations.